$title = htmlentities($title,ENT_NOQUOTES,@$encoding);
$keywords = htmlentities($keywords,ENT_NOQUOTES,@$encoding);

$content = array(
'post_title'=>$title,
'post_content'=>$body,
'post_type'=>'some_custom_post_type',
'post_status' => 'draft', // http://codex.wordpress.org/Post_Status
'mt_allow_comments'=>0, // 1 to allow comments
'mt_allow_pings'=>0, // 1 to allow trackbacks
'mt_keywords'=>$keywords,
'categories'=>array($category),
'custom_fields' => array($customfields)
);

// Create the client object
$client = new IXR_Client('http://example.com/xmlrpc.php');
$username = "wp_username";
$password = "wp_username_password";

$params = array(0,$username,$password,$content,true); // Last parameter is 'true' which means post immediately, to save as draft set it as 'false'

if (!$client->query('wp.newPost', $params)) {
die('Something went wrong - '.$client->getErrorCode().' : '.$client->getErrorMessage().'');

}
else
{
$post_id = $client->getResponse();
echo 'Inserted with id'.$post_id;
$picture = '/full/path/to/pic.jpg';
$content = array(
'name' => basename($picture),
'type' => mime_content_type($picture),
'bits' => new IXR_Base64(file_get_contents($picture)),
true
);
if (!$client->query('metaWeblog.newMediaObject', 1, $username, $password, $content)) {
die('
Something went wrong - newMediaObject'.$client->getErrorCode().' : '.$client->getErrorMessage().'
');
}
else
{
$media = $client->getResponse();
$content = array(
'post_status' => 'publish',
'post_thumbnail' => $media['id']
);
if (!$client->query('wp.editPost', 0, $username, $password, $post_id, $content)) {
die('
Something went wrong editPost - '.$client->getErrorCode().' : '.$client->getErrorMessage().'
');
}
}
}